Tris-EDTA buffer is commonly used in molecular biology to re-suspend and/or dilute purified DNA or RNA. The buffering properties of Tris and metal chelating properties of EDTA help protect DNA and RNA.DNase/RNase not detected. 100 x concentrated aqueous solution. Tris-EDTA buffer is commonly used in molecular biology to re-suspend and/or dilute purified DNA or RNA. The buffering properties of Tris and metal chelating properties of EDTA help protect DNA and RNA.DNase/RNase not detected. 100 x concentrated aqueous solution.