Papain ≥6 000 USP-U/mg, Reag. Ph. Eur., lyophilized A non-specific endopeptidase from Papaya latex. Has a very wide substrate range and cleaves proteins more efficiently than trypsin, for example. Is capable of not only hydrolysing peptide bonds, but also acts effectively as an esterase and thiol-esterase. Unit definition 6.000 USP (Casein) Units is approx. 0,5 FIP-Units (BAEE-Units). One USP Unit of Papain activity releases the equivalent of 1 µg tyrosine form a specified casein substrate under assay conditions specified by the USP. Directions for use Working concentration: Dilution immediately before application in a buffer with approx. 5 mM L-Cysteine pH optimum: 6.0 Temperature optimum: 65 °C Activation and stabilization: EDTA, Cysteine and Dimercaptopropanol. DTT may be added in orderto increase activity. Not a medical device / Not an IVD product