Bromelain is a non-specific cysteine endopeptidase (thiol proteinase) suitable for degradation of proteins like casein, collagen, globulin, hemoglobin. It is used in blood group serology (1). The protease digests preferably at lysine, alanine, tyrosine and glycine. It has a temperature optimum at 50 - 65 °C and a pH optimum of 5 - 6. Bromelain is a non-specific cysteine endopeptidase (thiol proteinase) suitable for degradation of proteins like casein, collagen, globulin, hemoglobin. It is used in blood group serology (1). The protease digests preferably at lysine, alanine, tyrosine and glycine. It has a temperature optimum at 50 - 65 °C and a pH optimum of 5 - 6.