This antibody portfolio includes a wide range of tissue- & tumor-specific primary antibodies for basic research, product development and analysis of a variety of biological questions. The monoclonal antibodies are perfectly applicable for all cell or tissue biology studies and for the analysis of predictive markers in research. High epitope affinity Highly specific detection of the target protein Unconjugated Suitable for e.g. western blot, immunoprecipitation, ELISA & immunofluorescence anti-Desmoplakin 1/2 mouse monoclonal, DP 1 + 2-2.15 50 μg/ml, monoclonal, affinity purified DP1 + 2-2.15 shows distinct punctate membrane staining of different epithelia. Tumors specifically detected: primary and metastatic carcinoma and meningioma. Polypeptides reacting: desmoplakin 1 and 2 (Mr 250,000 and 215,000). The epitope recognized by clone DP1 + 2-2.15 is mapped to the N-terminus of the rod domain (Bornslaeger, E. A., 1996). Bornslaeger, E. A. Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly. J. Cell Biol. 134, 9851001 (1996). Application Immunocytochemistry (ICC): Assay dependent Immunohistochemistry (IHC) - frozen: 1:10-1:50 (1-5 μg/ml) Immunohistochemistry (IHC) - paraffin: 1:10-1:50 (1-5 μg/ml, microwave treatment recommended) Western Blot (WB): assay dependent IHC of mouse heart (copyright: PROGEN in cooperation with Uniklinik Heidelberg, Dr. Jochen Hess) IHC of human uvula (copyright: PROGEN in cooperation with Uniklinik Heidelberg, Dr. Jochen Hess) IHC of human uvula (copyright: PROGEN in cooperation with Uniklinik Heidelberg, Dr. Jochen Hess) Not a medical device / Not an IVD product