Adapted for use across diverse chemical handling environments, the Separation columns for HPLC, specifically the HPLC column NUCLEODUR ® C 18 Gravity, 1.8 μm, 100 mm, 3 mm, excel due to their high density C 18 phase based on high purity NUCLEODUR ® silica gel. This design suppresses unwanted polar interactions between the silica surface and the sample, making them particularly suitable for the separation of basic and other ionizable analytes. With enhanced pH stability, LC/MS suitability, and superior base deactivation, these columns are an ideal choice for method development and valuable for RP applications. Their recommended usage includes a wide range of compounds with ionizable functional groups, such as pharmaceuticals, antidepressants, anti-inflammatory drugs, herbicides, and more.

• Category: Separation columns for HPLC
• Pressure stability: 900 bar
• Temperature stability: 60 ° C
• Column shape: Analytical separation column
• Particle size: 1.8 µm
• Pore volume: 0.9 ml/g
• Separation principle: Reversed phase (RP)
• L x Ø internal (column): 100 x 3 mm
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Phase: C 18 Gravity
• Column volume: 0.7 ml
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Specific surface according to BET: 340 m²/g
• pH stability: 1,0-11,0
• Endcapped: yes
• Particle type: Fully porous particles (FPP)
• USP listing: L1
• Eluent in column: Acetonitrile - Water
• Column type: UHPLC column
• Pore size: 110 Å