Engineered for consistent performance, the HPLC Column Nucleodur® C 18 Pyramid, featuring a particle size of 3 μm and a length of 250 mm with an inner diameter of 4.6 mm, is designed for analytical separations. This fully porous particle (FPP) column offers a specific surface area of 340 m²/g and a pore size of 110 Å, ensuring efficient separation of complex mixtures. Its unique octadecyl (C 18 , ODS) modification with polar endcapping makes it suitable for aqueous eluents, making it an ideal choice for analyzing very polar compounds such as pharmaceutical raw materials, organic acids, penicillin antibiotics, and water-soluble vitamins.

• Category: Separation columns for HPLC
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• L x Ø internal (column): 250 x 4.6 mm
• Eluent in column: Acetonitrile - Water
• Separation principle: Reversed phase (RP)
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Pore size: 110 Å
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Pore volume: 0.9 ml/g
• Column type: HPLC column
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Temperature stability: 60 ° C
• pH stability: 1,0-9,0
• Column shape: Analytical separation column
• Specific surface according to BET: 340 m²/g
• Particle type: Fully porous particles (FPP)
• Phase: C 18 Pyramid
• Particle size: 3 µm
• Column volume: 4.15 ml
• Endcapped: yes
• Pressure stability: 600 bar
• USP listing: L1