Formulated to support synthetic operations, the Hplc Column Nucleodur® C 18 Gravity, 5 μm, 125 mm, 21 mm offers a reversed phase (RP) separation principle ideal for method development. With a particle size of 5 μm and a specific surface area of 340 m²/g, this preparative separation column provides excellent pressure stability up to 400 bar and temperature stability up to 60°C. Its high density C 18 phase, based on high purity NUCLEODUR® silica gel, features endcapping that suppresses unwanted polar interactions, making it suitable for separating basic and other ionizable analytes. Furthermore, its enhanced pH stability, LC/MS suitability, and superior base deactivation make it an excellent choice for RP applications across various industries including pharmaceuticals, agro

• Category: Separation columns for HPLC
• pH stability: 1,0-11,0
• USP listing: L1
• Endcapped: yes
• Column shape: Preparative separation column
• Pressure stability: 400 bar
• Pore size: 110 Å
• L x Ø internal (column): 125 x 21 mm
• Particle type: Fully porous particles (FPP)
• Column volume: 43 ml
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Particle size: 5 µm
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Column type: HPLC column
• Eluent in column: Acetonitrile - Water
• Pore volume: 0.9 ml/g
• Separation principle: Reversed phase (RP)
• Specific surface according to BET: 340 m²/g
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Phase: C 18 Gravity
• Temperature stability: 60 ° C
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals