Neomycin is a member of the aminoglycosides, aminoglycosidic aminocyclitols consisting of a six-membered aminocyclitol ring attached to aminosugar side chains through a glycosidic bond. Technical Advantage:  Effective against Gram-positive and -negative bacteria Neomycin, a nucleoside antibiotic and aminoglycoside, is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3'-terminal end of aminoacyl-tRNA.  It prevents growth of bacteria, protozoa, algae, and mammalian cells.  Organisms carrying the resistance gene puromycin acetyltransferase are effectively protected from this compound.  Neomycin is effective against Gram-negative and Gram-positive bacteria. Neomycin is a member of the aminoglycosides, aminoglycosidic aminocyclitols consisting of a six-membered aminocyclitol ring attached to aminosugar side chains through a glycosidic bond. Technical Advantage:  Effective against Gram-positive and -negative bacteria Neomycin, a nucleoside antibiotic and aminoglycoside, is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3'-terminal end of aminoacyl-tRNA.  It prevents growth of bacteria, protozoa, algae, and mammalian cells.  Organisms carrying the resistance gene puromycin acetyltransferase are effectively protected from this compound.  Neomycin is effective against Gram-negative and Gram-positive bacteria.