During the mature phase of process development and into manufacturing, closed system packaging would be necessary to maintain sterility and ease bioreactor loading. Corning microcarriers are also available in off-the-shelf and custom closed systems packaging. Tubing, connectors, and materials are customizable based on individual needs. During the mature phase of process development and into manufacturing, closed system packaging would be necessary to maintain sterility and ease bioreactor loading. Corning microcarriers are also available in off-the-shelf and custom closed systems packaging. Tubing, connectors, and materials are customizable based on individual needs.