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Aminoglycoside antibiotic, inhibitor of protein biosynthesis. It is active against gram negative and gram positive bacteria. Main component is Kanamycin A. Suitable for prevention of bacterial contamination in cell culture. Used in molecular biology for the selection of resistant bacteria.Activity: min. 750 U/mg. Easily soluble in water.Stock solution: 10 mg/ml in H2O, working solution: 100 µg/ml. Aminoglycoside antibiotic, inhibitor of protein biosynthesis. It is active against gram negative and gram positive bacteria. Main component is Kanamycin A. Suitable for prevention of bacterial contamination in cell culture. Used in molecular biology for the selection of resistant bacteria.Activity: min. 750 U/mg. Easily soluble in water.Stock solution: 10 mg/ml in H2O, working solution: 100 µg/ml.
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From Streptomyces albo-niger. Free base (Mr 471.5) 86 %. Inhibitor of protein biosynthesis. Causes premature termination of the nascent polypeptide chain by its action as aminoacyl-tRNA analog (in procaryotes and eucaryotes). From Streptomyces albo-niger. Free base (Mr 471.5) 86 %. Inhibitor of protein biosynthesis. Causes premature termination of the nascent polypeptide chain by its action as aminoacyl-tRNA analog (in procaryotes and eucaryotes).
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Aminoglycoside antibiotic from Streptomyces griseus. Blocks the initiation complex and causes misreading on ribosomes in protein synthesis. Inhibits function only of the 30S subunit. Min. 720 U/mg. Aminoglycoside antibiotic from Streptomyces griseus. Blocks the initiation complex and causes misreading on ribosomes in protein synthesis. Inhibits function only of the 30S subunit. Min. 720 U/mg.
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Aminoglycoside antibiotic complex from Micromonospora purpurea.Consists of closely related compounds: gentamycin C1, C1a, C2, C2a and C2b. Inhibits bacterial protein synthesis by binding to the ribosomal 30S subunit and causing misreading of mRNA (in a similar way as streptomycin).Broad spectrum antibiotic which inhibits growth of many gram positive and gram negative bacteria including strains which are resistant to chloramphenicol, kanamycin or tetracycline. Frequently used in cell culture, often in combination with amphotericin B, nystatin or penicillin G (1,3).Min. 590 U/mg gentamycin base/g. Aminoglycoside antibiotic complex from Micromonospora purpurea.Consists of closely related compounds: gentamycin C1, C1a, C2, C2a and C2b. Inhibits bacterial protein synthesis by binding to the ribosomal 30S subunit and causing misreading of mRNA (in a similar way as streptomycin).Broad spectrum antibiotic which inhibits growth of many gram positive and gram negative bacteria including strains which are resistant to chloramphenicol, kanamycin or tetracycline. Frequently used in cell culture, often in combination with amphotericin B, nystatin or penicillin G (1,3).Min. 590 U/mg gentamycin base/g.
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Glutarimide antibiotic isolated from Streptomyces griseus, active against fungi and yeasts, but not against bacteria. Inhibits eukaryotic protein synthesis by blocking the translocation step in the elongation cycle (1,3,8). Blocks translation of mRNA on cytosolic but not on mitochondrial or chloroplast ribosomes (2,4,6). Glutarimide antibiotic isolated from Streptomyces griseus, active against fungi and yeasts, but not against bacteria. Inhibits eukaryotic protein synthesis by blocking the translocation step in the elongation cycle (1,3,8). Blocks translation of mRNA on cytosolic but not on mitochondrial or chloroplast ribosomes (2,4,6).
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Polyene macrolide antibiotic isolated from Streptomyces noursei. Used in animal and plant cell cultures against fungi and yeasts. Forms complexes with ergosterol in the fungal cell membrane resulting in the formation of pores and loss of ions and small molecules. Polyene macrolide antibiotic isolated from Streptomyces noursei. Used in animal and plant cell cultures against fungi and yeasts. Forms complexes with ergosterol in the fungal cell membrane resulting in the formation of pores and loss of ions and small molecules.
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Bacteriostatic antibiotic isolated from strains of Streptomyces, active against gram positive and gram negative bacteria and also against intracellular microorganisms like Rickettsia and mycoplasma. Inhibits bacterial protein synthesis by preventing aminoacyl-RNA binding to the A-side of the 30S ribosomal subunit. Sample analysis (1,2). Used for the selection of resistant clones (3,4). Bacteriostatic antibiotic isolated from strains of Streptomyces, active against gram positive and gram negative bacteria and also against intracellular microorganisms like Rickettsia and mycoplasma. Inhibits bacterial protein synthesis by preventing aminoacyl-RNA binding to the A-side of the 30S ribosomal subunit. Sample analysis (1,2). Used for the selection of resistant clones (3,4).
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From Streptomyces albo-niger. Free base (Mr 471.5) 86 %. Inhibitor of protein biosynthesis. Causes premature termination of the nascent polypeptide chain by its action as aminoacyl-tRNA analog (in procaryotes and eucaryotes). From Streptomyces albo-niger. Free base (Mr 471.5) 86 %. Inhibitor of protein biosynthesis. Causes premature termination of the nascent polypeptide chain by its action as aminoacyl-tRNA analog (in procaryotes and eucaryotes).
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Bacteriostatic antibiotic isolated from strains of Streptomyces, active against gram positive and gram negative bacteria and also against intracellular microorganisms like Rickettsia and mycoplasma. Inhibits bacterial protein synthesis by preventing aminoacyl-RNA binding to the A-side of the 30S ribosomal subunit. Sample analysis (1,2). Used for the selection of resistant clones (3,4). Bacteriostatic antibiotic isolated from strains of Streptomyces, active against gram positive and gram negative bacteria and also against intracellular microorganisms like Rickettsia and mycoplasma. Inhibits bacterial protein synthesis by preventing aminoacyl-RNA binding to the A-side of the 30S ribosomal subunit. Sample analysis (1,2). Used for the selection of resistant clones (3,4).
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Chloramphenicol is an antibiotic, isolated from strains of Streptomyces venezuelae. It blocks bacterial protein synthesis by inhibiting the peptidyl transferase activity of the 50S ribosomal subunit. The antibiotic has a broad application range against gram positive and gram negative bacteria.Chloramphenicol is used for bacterial selection and plasmid amplification in molecular biology applications and as a selection agent for transformed cells containing chloramphenicol reistance genes.A stock solution opf 50 mg/ml in ethanol yield a clear, very faint yellow solution. For selection of chloramphenicol-resistant Escherichia coli a concentration of 30 - 50 µg/ml are typically used. Chloramphenicol is an antibiotic, isolated from strains of Streptomyces venezuelae. It blocks bacterial protein synthesis by inhibiting the peptidyl transferase activity of the 50S ribosomal subunit. The antibiotic has a broad application range against gram positive and gram negative bacteria.Chloramphenicol is used for bacterial selection and plasmid amplification in molecular biology applications and as a selection agent for transformed cells containing chloramphenicol reistance genes.A stock solution opf 50 mg/ml in ethanol yield a clear, very faint yellow solution. For selection of chloramphenicol-resistant Escherichia coli a concentration of 30 - 50 µg/ml are typically used.
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Aminoglycoside antibiotic complex. Inhibits protein biosynthesis by binding to the 30S subunit of bacterial ribosomes. Causes misreading of mRNA. Aminoglycoside antibiotic complex. Inhibits protein biosynthesis by binding to the 30S subunit of bacterial ribosomes. Causes misreading of mRNA.
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Chloramphenicol is an antibiotic, isolated from strains of Streptomyces venezuelae. It blocks bacterial protein synthesis by inhibiting the peptidyl transferase activity of the 50S ribosomal subunit. The antibiotic has a broad application range against gram positive and gram negative bacteria.Chloramphenicol is used for bacterial selection and plasmid amplification in molecular biology applications and as a selection agent for transformed cells containing chloramphenicol reistance genes.A stock solution opf 50 mg/ml in ethanol yield a clear, very faint yellow solution. For selection of chloramphenicol-resistant Escherichia coli a concentration of 30 - 50 µg/ml are typically used. Chloramphenicol is an antibiotic, isolated from strains of Streptomyces venezuelae. It blocks bacterial protein synthesis by inhibiting the peptidyl transferase activity of the 50S ribosomal subunit. The antibiotic has a broad application range against gram positive and gram negative bacteria.Chloramphenicol is used for bacterial selection and plasmid amplification in molecular biology applications and as a selection agent for transformed cells containing chloramphenicol reistance genes.A stock solution opf 50 mg/ml in ethanol yield a clear, very faint yellow solution. For selection of chloramphenicol-resistant Escherichia coli a concentration of 30 - 50 µg/ml are typically used.
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