Polyene macrolide antibiotic isolated from Streptomyces noursei. Used in animal and plant cell cultures against fungi and yeasts. Forms complexes with ergosterol in the fungal cell membrane resulting in the formation of pores and loss of ions and small molecules. Polyene macrolide antibiotic isolated from Streptomyces noursei. Used in animal and plant cell cultures against fungi and yeasts. Forms complexes with ergosterol in the fungal cell membrane resulting in the formation of pores and loss of ions and small molecules.