Reagents for Peptide Synthesis for Washing/Deprotection/Splitting

2474.3, Carl

N , N -Diisopropylethylamine (DIPEA) PEPTIPURE ® ≥99,5 %, for peptide synthesis Diisopropylethylamine (DIPEA) is a tertiary amine, which makes it a strong organic base with a pKa value of about 11. It is often used as a nucleophilic catalyst to promote the formation of peptide bonds in solid phase peptide synthesis (SPPS). DIPEA is often used in peptide synthesis because of its high basicity and low nucleophilicity. It can promote the reaction between the carboxyl group of the activated amino acid and the amine group of the growing peptide chain without affecting the formation of the peptide bond. In addition, DIPEA can improve the deprotection of amino acid residues during peptide synthesis by scavenging acidic impurities.

3478.2, Carl

Water doubly distilled

4483.3, Carl

4380.4, Carl

For easy opening of the ROTITAINER ® we recommend the barrel and keg key Tri-Sure ® (Art. No. 0398.1) from ROTH SELECTION. Video instructions can be found here and above in the product pictures. Acetonitrile ≥99,5 %, for synthesis

A529.7, Carl

N , N -Dimethylformamide (DMF) PEPTIPURE ® ≥99,8 %, for peptide synthesis N , N -Dimethylformamide (DMF) is a colourless, polar, aprotic solvent with a high boiling point that is frequently used in peptide synthesis. It is known for its ability to dissolve a wide range of organic and inorganic compounds. In peptide synthesis, DMF is used to dissolve amino acids and peptide coupling reagents such as N , N' -dicyclohexylcarbodiimide (DCC), which is essential for the formation of peptide bonds. DMF is also commonly used as a solvent for other reagents and additives used in peptide synthesis, e.g. bases such as diisopropylethylamine (DIPEA). The polar, aprotic nature of DMF makes it an excellent solvent for reactions involving polar or charged species. It can also act as a dehydrating agent, helping to remove water from reaction mixtures, which is essential in peptide synthesis where water can compete with the formation of peptide bonds.

2473.3, Carl

9691.2, Carl

9691.3, Carl

A529.3, Carl

N , N -Dimethylformamide (DMF) PEPTIPURE ® ≥99,8 %, for peptide synthesis N , N -Dimethylformamide (DMF) is a colourless, polar, aprotic solvent with a high boiling point that is frequently used in peptide synthesis. It is known for its ability to dissolve a wide range of organic and inorganic compounds. In peptide synthesis, DMF is used to dissolve amino acids and peptide coupling reagents such as N , N' -dicyclohexylcarbodiimide (DCC), which is essential for the formation of peptide bonds. DMF is also commonly used as a solvent for other reagents and additives used in peptide synthesis, e.g. bases such as diisopropylethylamine (DIPEA). The polar, aprotic nature of DMF makes it an excellent solvent for reactions involving polar or charged species. It can also act as a dehydrating agent, helping to remove water from reaction mixtures, which is essential in peptide synthesis where water can compete with the formation of peptide bonds.

3617.4, Carl

P089.1, Carl

4380.2, Carl