Sodium acetate buffer solution suitable for the use in the purification and precipitation of nucleic acids, protein crystallization, staining of gels in protein electrophoresis and HPLC. Sodium acetate solution has a buffering range from pH 3.6 - 5.6.DNase/RNase not detected. Sodium acetate buffer solution suitable for the use in the purification and precipitation of nucleic acids, protein crystallization, staining of gels in protein electrophoresis and HPLC. Sodium acetate solution has a buffering range from pH 3.6 - 5.6.DNase/RNase not detected.