Designed with efficiency in synthetic processes in mind, the Hplc Column Nucleodur ® PFP, 5 μm, 250 mm, 3 mm features a pentafluorophenyl-propyl modification on high purity NUCLEODUR ® silica gel. This hydrophobic phase offers an alternative selectivity compared to traditional C 18 modifications. With a specific surface area of 340 m²/g, it provides four retention mechanisms including polar interactions (H bonds), dipole-dipole interactions, π-π interactions, and hydrophobic interactions. Its recommended applications include antibiotics, aromatic and unsaturated compounds, basic compounds, suitable for LC-MS, halogenated compounds, isomers, pharmaceutical products, phenols, and especially for polar compounds. It boasts a pressure stability of

• Category: Separation columns for HPLC
• L x Ø internal (column): 250 x 3 mm
• Pressure stability: 600 bar
• Specific surface according to BET: 340 m²/g
• Endcapped: yes
• Recommended application(s): Antibiotics Aromatic and unsaturated compounds Basic compounds Suitable for LC-MS Halogenated compounds Isomers Pharmaceutical products Phenols Especially for polar compounds
• Surface chemistry: Pentafluorophenylpropyl (PFP) modification
• Interactions / retention mechanism: polar (H-bond), dipole-dipole, π-π and hydrophobic
• Pore size: 110 Å
• pH stability: 1,0-9,0
• USP listing: L43
• Eluent in column: Acetonitrile - Water
• Pore volume: 0.9 ml/g
• Application Database (Macherey-Nagel): HPLC
• Separation principle: Reversed phase (RP)
• Phase: PFP
• Particle type: Fully porous particles (FPP)
• Temperature stability: 60 ° C
• Column type: HPLC column
• Column volume: 1.75 ml
• Particle size: 5 µm
• Column shape: Analytical separation column