Optimized for controlled laboratory processes, the Hplc Column Nucleodur® C 8 Gravity offers exceptional performance for reversed phase liquid chromatography (LC/RP). With a particle size of 5 μm, this fully porous particle (FPP) column features a high density C 8 phase based on high purity NUCLEODUR® silica gel that ensures minimal polar interactions between the silica surface and the sample. Its enhanced pH stability, LC/MS suitability, and superior base deactivation make it an ideal choice for method development and valuable for RP applications, especially for separating basic and other ionizable analytes. The column's specific surface area of 340 m²/g, combined with its pressure stability up to 600 bar and temperature stability at 60°C, ensures reliable and reproducible results in various applications, including pharmaceuticals

• Category: Separation columns for HPLC
• Interactions / retention mechanism: hydrophobic (van der Waals)
• pH stability: 1,0-11,0
• Temperature stability: 60 ° C
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• USP listing: L7
• Particle type: Fully porous particles (FPP)
• Pore size: 110 Å
• Phase: C 8 Gravity
• Endcapped: yes
• Column shape: Analytical separation column
• Eluent in column: Acetonitrile - Water
• Separation principle: Reversed phase (RP)
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Pressure stability: 600 bar
• Pore volume: 0.9 ml/g
• Column volume: 0.15 ml
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Particle size: 5 µm
• Column type: HPLC column
• Specific surface according to BET: 340 m²/g
• L x Ø internal (column): 50 x 2 mm