Intended for structured formulation workflows, the Hplc Column Nucleodur® C 18 Gravity, 5 μm, 150 mm, 3 mm offers exceptional performance for the separation of basic and ionizable analytes due to its endcapped C 18 phase based on high purity NUCLEODUR® silica gel. With an enhanced pH stability ranging from 1 to 11, this column is ideal for method development and RP applications, making it a valuable tool for separating pharmaceuticals, antidepressants, anti-inflammatory drugs, herbicides, immunosuppressants, and various other compounds with ionizable functional groups. Its particle size of 5 μm ensures efficient separation while maintaining pressure stability up to 600 bar and temperature stability at 60° Celsius. Additionally, the column's

• Category: Separation columns for HPLC
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Pressure stability: 600 bar
• pH stability: 1,0-11,0
• USP listing: L1
• Phase: C 18 Gravity
• Particle type: Fully porous particles (FPP)
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• L x Ø internal (column): 150 x 3 mm
• Temperature stability: 60 ° C
• Separation principle: Reversed phase (RP)
• Specific surface according to BET: 340 m²/g
• Column type: HPLC column
• Pore size: 110 Å
• Column volume: 1.05 ml
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Particle size: 5 µm
• Eluent in column: Acetonitrile - Water
• Endcapped: yes
• Column shape: Analytical separation column
• Pore volume: 0.9 ml/g