Engineered for consistent performance, the HPLC column NUCLEODUR ® C 18 Gravity, featuring a 3 μm particle size and a 250 mm length, is designed for optimal separation of various compounds, especially those with ionizable functional groups like basic pharmaceuticals and pesticides. Its endcapped C 18 Gravity phase, based on high purity NUCLEODUR ® silica gel, minimizes unwanted polar interactions, making it ideal for RP applications and method development. With a pH stability range of 1-11, this column is well-suited for extreme pH values, offering LC/MS compatibility and superior base deactivation.

• Category: Separation columns for HPLC
• Interactions / retention mechanism: hydrophobic (van der Waals)
• USP listing: L1
• Pore volume: 0.9 ml/g
• Temperature stability: 60 ° C
• Particle size: 3 µm
• Pore size: 110 Å
• Eluent in column: Acetonitrile - Water
• pH stability: 1,0-11,0
• Column volume: 1.75 ml
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Column shape: Analytical separation column
• Particle type: Fully porous particles (FPP)
• Pressure stability: 600 bar
• Application Database (Macherey-Nagel): HPLC
• Phase: C 18 Gravity
• Column type: HPLC column
• Separation principle: Reversed phase (RP)
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Endcapped: yes
• L x Ø internal (column): 250 x 3 mm
• Specific surface according to BET: 340 m²/g