Widely applied in chemical workflows, separation columns for HPLC play an essential role in the identification and quantification of various substances. One such column is the HPLC Column Nucleodur® CN-RP, 5 μm, 125 mm, 4 mm. This column features a cyanopropyl phase, which offers a unique retention behavior due to its intermediate polarity. It exhibits distinct selectivity for polar organic compounds and molecules containing π electron systems, making it suitable for analyzing substances like tricyclic antidepressants, steroids, and molecules with π-electron systems. With a pH stability range of 1.0-8.0 and temperature stability up to 60°C, this column ensures reliable results under diverse conditions. Its specific surface area according to BET is 340 m²/g, providing

• Category: Separation columns for HPLC
• Pore volume: 0.9 ml/g
• Pressure stability: 600 bar
• Column volume: 1.56 ml
• pH stability: 1,0-8,0
• Endcapped: no
• Column shape: Analytical separation column
• Particle size: 5 µm
• L x Ø internal (column): 125 x 4 mm
• Recommended application(s): Molecules containing π-electron systems Organic acids Steroids Tricyclic antidepressants
• USP listing: L10
• Column type: HPLC column
• Pore size: 110 Å
• Specific surface according to BET: 340 m²/g
• Phase: CN-RP
• Separation principle: Multi-mode (NP and RP), Reversed phase (RP)
• Temperature stability: 60 ° C
• Particle type: Fully porous particles (FPP)
• Eluent in column: Acetonitrile - Water
• Interactions / retention mechanism: π-π and polar (H bond), hydrophobic
• Application Database (Macherey-Nagel): HPLC
• Surface chemistry: Cyano, nitrile (CN) modification