Developed for demanding processing applications, the HPLC Column Nucleodur® C 8 Gravity, 5 μm, 125 mm, 4 mm offers exceptional performance in reversed phase separations. With a high density C 8 phase based on high purity NUCLEODUR® silica gel, this column suppresses unwanted polar interactions, making it ideal for the separation of basic and other ionizable analytes. Its enhanced pH stability, LC/MS suitability, and superior base deactivation make it an excellent choice for method development and valuable for RP applications. The column's specific surface area of 340 m²/g ensures efficient separation, while its pressure stability of 600 bar and temperature stability of 60° C ensure durability under harsh conditions. Recommended applications include but are not limited to pharmaceuticals, antidepressants, anti-

• Category: Separation columns for HPLC
• Column type: HPLC column
• USP listing: L7
• Pressure stability: 600 bar
• Particle type: Fully porous particles (FPP)
• Pore size: 110 Å
• pH stability: 1,0-11,0
• Column volume: 1.56 ml
• Pore volume: 0.9 ml/g
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Separation principle: Reversed phase (RP)
• Temperature stability: 60 ° C
• Eluent in column: Acetonitrile - Water
• Phase: C 8 Gravity
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Particle size: 5 µm
• L x Ø internal (column): 125 x 4 mm
• Application Database (Macherey-Nagel): HPLC SPE
• Specific surface according to BET: 340 m²/g
• Endcapped: yes
• Column shape: Analytical separation column
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals