Engineered for consistent performance, the Hplc Column Nucleodur ® C 8 Gravity, 250 Mm, 21 Mm is designed for use in reversed phase (RP) separations, making it ideal for the separation of basic and other ionizable analytes. Its high density C 8 phase, based on high purity NUCLEODUR ® silica gel, features endcapping that suppresses unwanted polar interactions, enhancing its pH stability, LC/MS suitability, and superior base deactivation. This makes it an excellent choice for method development and valuable for RP applications. With a particle size of 5 μm, fully porous particles (FPP), and a pressure stability of 400 bar, this preparative separation column offers reliable performance under various conditions.

• Category: Separation columns for HPLC
• USP listing: L7
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• L x Ø internal (column): 250 x 21 mm
• Phase: C 8 Gravity
• Endcapped: yes
• Particle type: Fully porous particles (FPP)
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Column volume: 87 ml
• Column shape: Preparative separation column
• Pore volume: 0.9 ml/g
• Particle size: 5 µm
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Temperature stability: 60 ° C
• Column type: HPLC column
• Eluent in column: Acetonitrile - Water
• Pore size: 110 Å
• Separation principle: Reversed phase (RP)
• Specific surface according to BET: 340 m²/g
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Pressure stability: 400 bar
• pH stability: 1,0-11,0