Widely applied in chemical workflows, the HPLC column NUCLEODUR® C 8 Gravity offers exceptional performance for reversed-phase separations. Its high-density C 8 phase, based on high-purity NUCLEODUR® silica gel, provides excellent pH stability, making it ideal for use with basic and ionizable analytes. The endcapped nature of this column suppresses unwanted polar interactions, enhancing its suitability for LC/MS applications. With a particle size of 3 μm and a specific surface area of 340 m²/g, this column delivers efficient separations while maintaining pressure stability up to 600 bar. Recommended applications include the separation of pharmaceuticals, herbicides, and immunosuppressants, among others.

• Category: Separation columns for HPLC
• Column volume: 0.53 ml
• USP listing: L7
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Temperature stability: 60 ° C
• Pore volume: 0.9 ml/g
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Phase: C 8 Gravity
• Pressure stability: 600 bar
• pH stability: 1,0-11,0
• Particle size: 3 µm
• Pore size: 110 Å
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Column type: HPLC column
• Particle type: Fully porous particles (FPP)
• L x Ø internal (column): 75 x 3 mm
• Eluent in column: Acetonitrile - Water
• Endcapped: yes
• Column shape: Analytical separation column
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Specific surface according to BET: 340 m²/g
• Separation principle: Reversed phase (RP)