Nintedanib

Nintedanib is distinguished by its stable chemical profile, characterized by the empirical formula C31H33O4N5 and a molecular weight of 539,63 g/mol. This compound exhibits a Storage temp. range of +2 to +8 °C. For this specific SKU, it is available in a specified purity and form. Nintedanib is a potent tyrosine kinase inhibitor, particularly effective against fibroblast growth factor receptors FGFR1, FGFR2, and FGFR3, making it an essential tool in cancer research and treatment. It also demonstrates activity against vascular endothelial growth factor receptor VEGFR1, VEGFR2, and VEGFR3, contributing to its antiangiogenic properties. Additionally, nintedanib has been shown to inhibit platelet-derived growth factor receptor PDGFRα and PDGFRβ, which may have implications in fibrotic diseases.

• CAS Number: 656247-17-5
• Molecular Weight: 539,63 g/mol
• Flash Point: 402,7 °C
• Empirical formula: C31H33O4N5
• Storage temp.: +2 to +8 °C
• Melting point (mp): 240 °C