N,N-Dimethylacetamide (CAS 127-19-5) is a reference substance for gas chromatography (GC), categorized under Reference Substances for GC. It belongs to the substance group Carboxylic acid amides and has a Molecular Weight of 87.12 g/mol. In the workplace, it requires various precautions such as prohibiting smoking, no admittance for unauthorized persons, no eating and drinking, and wearing safety equipment like goggles and gloves. The European Union has set binding occupational exposure limits for this compound, including an 8-hour limit value of 36 mg/m3 (10 ppm) and a short-term limit value of 72 mg/m3 (20 ppm).

• CAS Number: 127-19-5
• Molecular Formula: C4H9NO
• Molecular Weight: 87.12
• Exact Mass: 87.068413911
• Boiling Point: 329 to 331 °F at 760 mmHg (NTP, 1992)
• Melting Point: -4 °F (NTP, 1992)
• Density: 3.01 (Air= 1)
• GHS Signal Word: Danger
• Hazard Statements:
• H312: Harmful in contact with skin [Warning Acute toxicity, dermal]
• H227: Combustible liquid [Warning Flammable liquids]
• H350: May cause cancer [Danger Carcinogenicity]
• H351: Suspected of causing cancer [Warning Carcinogenicity]
• H320: Causes eye irritation [Warning Serious eye damage/eye irritation]