Configured for stable performance in synthesis settings, the HPLC Column Nucleodur® C 18 Pyramid offers a unique combination of features. With a particle size of 1.8 μm, it delivers exceptional pressure stability up to 900 bar and temperature resistance up to 60°C. Its fully porous particles (FPP) ensure a specific surface area of 340 m²/g, providing ample interaction sites for hydrophobic and polar (H bonds) interactions. This UHPLC column's pore size of 110 Å and pore volume of 0.9 ml/g facilitate efficient separations, while its polar endcapping makes it suitable for aqueous eluents, earning it the nickname 'aqua column'. Ideal for analyzing pharmaceutical raw materials, very polar compounds, and complexing agents, among

• Category: Separation columns for HPLC
• Separation principle: Reversed phase (RP)
• Column shape: Analytical separation column
• Endcapped: yes
• Eluent in column: Acetonitrile - Water
• USP listing: L1
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Column volume: 0.1 ml
• Specific surface according to BET: 340 m²/g
• Pore volume: 0.9 ml/g
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Column type: UHPLC column
• Particle size: 1.8 µm
• Phase: C 18 Pyramid
• L x Ø internal (column): 30 x 2 mm
• Pore size: 110 Å
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• pH stability: 1,0-9,0
• Pressure stability: 900 bar
• Temperature stability: 60 ° C
• Particle type: Fully porous particles (FPP)
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping