Adapted for use across diverse chemical handling environments, the HPLC column NUCLEODUR® C 8 Gravity offers exceptional versatility in separating various compounds with ionizable functional groups. Its high density C 8 phase, based on high purity NUCLEODUR® silica gel, features endcapping that minimizes unwanted polar interactions, making it ideal for the separation of basic and other ionizable analytes. With an enhanced pH stability range of 1.0-11.0, this column demonstrates LC/MS suitability and superior base deactivation, making it a valuable asset for RP applications and method development.

• Category: Separation columns for HPLC
• Phase: C 8 Gravity
• Eluent in column: Acetonitrile - Water
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Pore size: 110 Å
• L x Ø internal (column): 250 x 4 mm
• Column volume: 3.15 ml
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• USP listing: L7
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Column shape: Analytical separation column
• Particle type: Fully porous particles (FPP)
• Pressure stability: 600 bar
• Particle size: 3 µm
• Column type: HPLC column
• Temperature stability: 60 ° C
• pH stability: 1,0-11,0
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Endcapped: yes
• Separation principle: Reversed phase (RP)
• Pore volume: 0.9 ml/g
• Specific surface according to BET: 340 m²/g