Designed with efficiency in synthetic processes in mind, the Separation columns for HPLC category includes the HPLC column NUCLEODUR ® C 8 Gravity, 125 MM, 10 MM. This particular model features a C 8 Gravity phase, a high density C 8 phase based on high purity NUCLEODUR ® silica gel that suppresses unwanted polar interactions between the silica surface and the sample, making it ideal for the separation of basic and other ionizable analytes. With an enhanced pH stability, LC/MS suitability, and superior base deactivation (BDS), this column is a valuable asset for RP applications, especially in method development.

• Category: Separation columns for HPLC
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Particle type: Fully porous particles (FPP)
• Particle size: 5 µm
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Column volume: 9.8 ml
• Specific surface according to BET: 340 m²/g
• Eluent in column: Acetonitrile - Water
• USP listing: L7
• Endcapped: yes
• L x Ø internal (column): 125 x 10 mm
• pH stability: 1,0-11,0
• Pore volume: 0.9 ml/g
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Temperature stability: 60 ° C
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Column type: HPLC column
• Phase: C 8 Gravity
• Pore size: 110 Å
• Pressure stability: 400 bar
• Separation principle: Reversed phase (RP)
• Column shape: Preparative separation column