A reliable solution for controlled synthesis, "Hplc Column Nucleodur ® C 18 Gravity, 5 μm, 125 Mm, 4 Mm" belongs to the category of Separation columns for HPLC. Featuring a high density C 18 phase based on high purity NUCLEODUR ® silica gel, this column offers excellent pH stability, LC/MS suitability, and superior base deactivation (BDS). It is an ideal choice for method development and valuable for RP applications due to its ability to separate basic and other ionizable analytes. With a particle size of 5 μm, it provides pressure stability up to 600 bar and temperature stability up to 60°C. Its recommended applications include pharmaceuticals, pesticides, anti-inflammatory drugs, and herbicides, among

• Category: Separation columns for HPLC
• Specific surface according to BET: 340 m²/g
• USP listing: L1
• Column volume: 1.56 ml
• Column shape: Analytical separation column
• Column type: HPLC column
• Endcapped: yes
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Temperature stability: 60 ° C
• Pressure stability: 600 bar
• Pore size: 110 Å
• L x Ø internal (column): 125 x 4 mm
• Particle size: 5 µm
• Eluent in column: Acetonitrile - Water
• Phase: C 18 Gravity
• Interactions / retention mechanism: hydrophobic (van der Waals)
• pH stability: 1,0-11,0
• Particle type: Fully porous particles (FPP)
• Application Database (Macherey-Nagel): HPLC SPE
• Separation principle: Reversed phase (RP)
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Pore volume: 0.9 ml/g