Widely applied in chemical workflows, the HPLC Column Nucleodur® C 18 Pyramid offers exceptional performance for separating very polar compounds such as pharmaceutical raw materials, organic acids, and nucleic acid bases. This fully porous particle (FPP) column features a 3 μm particle size, 1.25 ml column volume, and 110 Å pore size, ensuring optimal pressure stability up to 600 bar and temperature resistance up to 60°C. Its unique octadecyl (C 18 , ODS) modification with polar endcapping allows it to function effectively with both hydrophobic and polar interactions (H bonds), making it particularly suitable for aqueous eluents. With a specific surface area of 340 m²/g according to BET, this analytical separation column delivers reliable results for applications

• Category: Separation columns for HPLC
• Endcapped: yes
• Particle type: Fully porous particles (FPP)
• Particle size: 3 µm
• Temperature stability: 60 ° C
• Phase: C 18 Pyramid
• L x Ø internal (column): 100 x 4 mm
• Eluent in column: Acetonitrile - Water
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Pressure stability: 600 bar
• Pore volume: 0.9 ml/g
• Specific surface according to BET: 340 m²/g
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• pH stability: 1,0-9,0
• Pore size: 110 Å
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Column type: HPLC column
• Column shape: Analytical separation column
• Column volume: 1.25 ml
• USP listing: L1
• Separation principle: Reversed phase (RP)