Engineered to maintain reliability in process-driven workflows, the HPLC Column Nucleodur® C 18 Pyramid offers exceptional performance in liquid chromatography applications. This fully porous particle (FPP) column features a C 18 Pyramid phase, which is known for its polar endcapping, making it ideal for aqueous eluents. With a pore size of 110 Å and a specific surface area of 340 m²/g, it ensures efficient separation of very polar compounds such as pharmaceutical raw materials, organic acids, and penicillin antibiotics. Its pressure stability of up to 600 bar and temperature tolerance of 60°C make it versatile for various experimental conditions. Recommended for use with acetonitrile-water eluent, this HPLC column delivers consistent results in complexing agents

• Category: Separation columns for HPLC
• Temperature stability: 60 ° C
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Column shape: Analytical separation column
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Phase: C 18 Pyramid
• Particle size: 3 µm
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Specific surface according to BET: 340 m²/g
• Particle type: Fully porous particles (FPP)
• pH stability: 1,0-9,0
• Pore volume: 0.9 ml/g
• L x Ø internal (column): 125 x 4 mm
• Pore size: 110 Å
• Column volume: 1.56 ml
• Endcapped: yes
• Application Database (Macherey-Nagel): HPLC
• Pressure stability: 600 bar
• Eluent in column: Acetonitrile - Water
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Separation principle: Reversed phase (RP)
• Column type: HPLC column
• USP listing: L1