Built to deliver predictable results in synthesis routines, the Hplc Column Nucleodur ® PFP, 3 μm, 250 mm, 4 mm offers exceptional versatility as a reversed-phase separation column. Featuring a pentafluorophenylpropyl (PFP) modification on high-purity NUCLEODUR ® silica gel, this column provides an alternative selectivity compared to traditional C18 modifications. Its unique surface chemistry supports four retention mechanisms—polar interactions (H bonds), dipole-dipole interactions, π-π interactions, and hydrophobic interactions—making it suitable for a wide range of applications, including aromatic and unsaturated compounds, basic compounds, halogenated compounds, isomers, pharmaceutical products, phenols, and especially polar compounds. Additionally, its low bleeding characteristics

• Category: Separation columns for HPLC
• Separation principle: Reversed phase (RP)
• Particle size: 3 µm
• Column volume: 3.15 ml
• Eluent in column: Acetonitrile - Water
• Pore size: 110 Å
• Specific surface according to BET: 340 m²/g
• Pressure stability: 600 bar
• USP listing: L43
• L x Ø internal (column): 250 x 4 mm
• Pore volume: 0.9 ml/g
• Recommended application(s): Antibiotics Aromatic and unsaturated compounds Basic compounds Suitable for LC-MS Halogenated compounds Isomers Pharmaceutical products Phenols Especially for polar compounds
• Endcapped: yes
• Column type: HPLC column
• Interactions / retention mechanism: polar (H-bond), dipole-dipole, π-π and hydrophobic
• pH stability: 1,0-9,0
• Temperature stability: 60 ° C
• Particle type: Fully porous particles (FPP)
• Surface chemistry: Pentafluorophenylpropyl (PFP) modification
• Column shape: Analytical separation column
• Phase: PFP