Optimized for controlled laboratory processes, the Hplc Column Nucleodur ® C 18 Gravity, 5 μm, 125 mm, 4.6 mm features a high density C 18 phase based on high purity NUCLEODUR ® silica gel. Its endcapping suppresses unwanted polar interactions, making it ideal for separating basic and other ionizable analytes. With enhanced pH stability, LC/MS suitability, and superior base deactivation, this column is an excellent choice for method development and valuable for RP applications. It comes packaged with an analytical HPLC column, instruction leaflet, and certificate of analysis.

• Category: Separation columns for HPLC
• Particle size: 5 µm
• Specific surface according to BET: 340 m²/g
• Temperature stability: 60 ° C
• USP listing: L1
• Endcapped: yes
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Column volume: 2.06 ml
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Separation principle: Reversed phase (RP)
• Column shape: Analytical separation column
• Pore size: 110 Å
• Column type: HPLC column
• pH stability: 1,0-11,0
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Phase: C 18 Gravity
• Pressure stability: 600 bar
• Pore volume: 0.9 ml/g
• L x Ø internal (column): 125 x 4.6 mm
• Eluent in column: Acetonitrile - Water
• Particle type: Fully porous particles (FPP)
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Application Database (Macherey-Nagel): HPLC