HPLC column NUCLEODUR ® C 18 Gravity, 5 µm, 50 mm, 4.6 mm

Produced to ensure dependable processing results, the Hplc Column Nucleodur® C 18 Gravity, 5 μm, 50 mm, 4.6 mm features a high density C 18 phase based on high purity NUCLEODUR® silica gel. Its endcapping suppresses unwanted polar interactions between the silica surface and the sample, making it ideal for the separation of basic and other ionizable analytes. With enhanced pH stability, LC/MS suitability, and superior base deactivation, this column is a valuable asset for RP applications and method development. It comes packaged with an analytical HPLC column, instruction leaflet, and certificate of analysis.

• Category: Separation columns for HPLC
• Column type: HPLC column
• pH stability: 1,0-11,0
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Separation principle: Reversed phase (RP)
• L x Ø internal (column): 50 x 4.6 mm
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Column volume: 0.83 ml
• Specific surface according to BET: 340 m²/g
• Particle type: Fully porous particles (FPP)
• Eluent in column: Acetonitrile - Water
• Phase: C 18 Gravity
• Application Database (Macherey-Nagel): HPLC
• Column shape: Analytical separation column
• Temperature stability: 60 ° C
• Pore size: 110 Å
• Endcapped: yes
• Pore volume: 0.9 ml/g
• Pressure stability: 600 bar
• Particle size: 5 µm
• Interactions / retention mechanism: hydrophobic (van der Waals)
• USP listing: L1