Formulated to support synthetic operations, the Hplc Column Nucleodur® C 18 Gravity, 5 μm, 250 mm, 10 mm offers a reversed phase (RP) separation principle that excels in separating compounds with ionizable functional groups, making it ideal for applications involving basic pharmaceuticals, antidepressants, anti-inflammatory drugs, herbicides, immunosuppressants, and various pharmaceutical products. Its high density C 18 phase, based on high purity NUCLEODUR® silica gel, features endcapping to minimize unwanted polar interactions, ensuring excellent performance for RP applications. With a temperature stability of up to 60°C and pressure resistance of 400 bar, this column ensures durability under demanding conditions.

• Category: Separation columns for HPLC
• Column type: HPLC column
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• USP listing: L1
• Phase: C 18 Gravity
• Pore volume: 0.9 ml/g
• L x Ø internal (column): 250 x 10 mm
• Separation principle: Reversed phase (RP)
• Column shape: Preparative separation column
• Endcapped: yes
• Particle size: 5 µm
• pH stability: 1,0-11,0
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Column volume: 20 ml
• Pore size: 110 Å
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Specific surface according to BET: 340 m²/g
• Eluent in column: Acetonitrile - Water
• Temperature stability: 60 ° C
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Pressure stability: 400 bar
• Particle type: Fully porous particles (FPP)