Manufactured to meet research and production requirements, this HPLC column is part of the NUCLEODUR® C 18 ec series, designed for routine analyses and upscaling for preparative HPLC. With a particle size of 5 μm and a pore size of 110 Å, it offers a wide range of applications, including the separation of basic, neutral, or acidic drugs, derivatized amino acids, pesticides, fat-soluble vitamins, aldehydes, and ketones, among others. This column features a medium density monomeric octadecyl (C 18, ODS) modification, ensuring hydrophobic interactions and some residual silanol interactions. It is compatible with an eluent mixture of acetonitrile and water, and its temperature stability extends up to 60°C.

• Category: Separation columns for HPLC
• Temperature stability: 60 ° C
• Column shape: Analytical separation column
• Column type: HPLC column
• USP listing: L1
• Pore size: 110 Å
• Eluent in column: Acetonitrile - Water
• L x Ø internal (column): 250 x 4 mm
• Particle type: Fully porous particles (FPP)
• Particle size: 5 µm
• Interactions / retention mechanism: hydrophobic (van der Waals interactions), some residual silanol interactions
• Separation principle: Reversed phase (RP)
• pH stability: 1,0-9,0
• Endcapped: yes
• Pore volume: 0.9 ml/g
• Application Database (Macherey-Nagel): HPLC SPE
• Specific surface according to BET: 340 m²/g
• Pressure stability: 600 bar
• Recommended application(s): Routine analyses Aldehydes Basic, neutral or acidic drugs Derivatised amino acids Fat-soluble vitamins Ketones Pesticides Phenolic compounds
• Phase: C 18 ec
• Column volume: 3.15 ml
• Surface chemistry: Medium density monomeric octadecyl (C 18 , ODS) modification
• Similar phases: NUCLEOSIL ® C 18 Spherisorb ® ODS II Symmetry ® C 18 Hypersil™ ODS Inertsil ® ODS II Kromasil ® C 18 LiChrospher ® RP 18