Designed with efficiency in synthetic processes in mind, the Hplc Column Nucleodur ® C 18 Gravity, 1.8 μm, 75 mm, 2 mm features a UHPLC column with a C 18 Gravity phase based on high purity NUCLEODUR ® silica gel. Its endcapping suppresses unwanted polar interactions between the silica surface and the sample, making it ideal for separating basic and other ionizable analytes. With an enhanced pH stability, LC/MS suitability, and superior base deactivation, this column is a valuable asset for RP applications and method development. It boasts a specific surface area of 340 m²/g, a particle size of 1.8 μm, and a temperature stability of up to 60 °C.

• Category: Separation columns for HPLC
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Specific surface according to BET: 340 m²/g
• Column shape: Analytical separation column
• Pore size: 110 Å
• Temperature stability: 60 ° C
• Pressure stability: 900 bar
• Pore volume: 0.9 ml/g
• L x Ø internal (column): 75 x 2 mm
• Eluent in column: Acetonitrile - Water
• pH stability: 1,0-11,0
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Particle size: 1.8 µm
• Separation principle: Reversed phase (RP)
• Column volume: 0.22 ml
• Column type: UHPLC column
• USP listing: L1
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Endcapped: yes
• Phase: C 18 Gravity
• Particle type: Fully porous particles (FPP)