Produced for stability across temperature-sensitive applications, this HPLC column features a C 18 Gravity phase made from high purity NUCLEODUR® silica gel. Endcapped to suppress unwanted polar interactions, it's ideal for separating basic and ionizable analytes. With enhanced pH stability, LC/MS suitability, and superior base deactivation, it excels in method development and is valuable for RP applications. Its particle size of 3 μm ensures pressure stability up to 600 bar and temperature stability up to 60°C. Suitable for a wide range of applications including pharmaceuticals, pesticides, and herbicides, this column is an excellent choice for lab professionals seeking reliable performance in their chromatography work.

• Category: Separation columns for HPLC
• pH stability: 1,0-11,0
• Phase: C 18 Gravity
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Eluent in column: Acetonitrile - Water
• Application Database (Macherey-Nagel): HPLC
• Separation principle: Reversed phase (RP)
• USP listing: L1
• Column type: HPLC column
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Pore size: 110 Å
• L x Ø internal (column): 100 x 4.6 mm
• Particle size: 3 µm
• Endcapped: yes
• Pressure stability: 600 bar
• Specific surface according to BET: 340 m²/g
• Particle type: Fully porous particles (FPP)
• Column shape: Analytical separation column
• Column volume: 1.65 ml
• Temperature stability: 60 ° C
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Pore volume: 0.9 ml/g
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS