Intended for structured formulation workflows, the Hplc Column Nucleodur ® C 18 Gravity, 5 μm, 125 mm, 10 mm offers exceptional performance for reversed-phase liquid chromatography (LC/LC). Its high-density C 18 phase based on high-purity NUCLEODUR ® silica gel ensures minimal interaction with basic and ionizable analytes, making it ideal for method development and RP applications. With a specific surface area of 340 m²/g and a pore size of 110 Å, this column provides excellent separation capabilities while maintaining pressure stability up to 400 bar and temperature stability up to 60 °C. Furthermore, its enhanced pH stability ranging from 1 to 11, coupled with its superior base deactivation, makes it an optimal choice for separating a wide

• Category: Separation columns for HPLC
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Eluent in column: Acetonitrile - Water
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• pH stability: 1,0-11,0
• Pore volume: 0.9 ml/g
• Particle size: 5 µm
• USP listing: L1
• Pore size: 110 Å
• Pressure stability: 400 bar
• Separation principle: Reversed phase (RP)
• Endcapped: yes
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Column type: HPLC column
• Column volume: 9.8 ml
• Specific surface according to BET: 340 m²/g
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• L x Ø internal (column): 125 x 10 mm
• Temperature stability: 60 ° C
• Particle type: Fully porous particles (FPP)
• Column shape: Preparative separation column
• Phase: C 18 Gravity