Widely applied in chemical workflows, the HPLC column NUCLEODUR ® C 18 Gravity, featuring a 3 μm particle size and a 125 mm length, is an essential tool for reversed-phase separations. Its high-density C 18 phase, based on high-purity NUCLEODUR ® silica gel, offers excellent pH stability ranging from 1 to 11, making it ideal for separating basic and ionizable analytes. The endcapping process further suppresses unwanted polar interactions, enhancing its LC/MS suitability and superior base deactivation, making it a preferred choice for method development and RP applications.

• Category: Separation columns for HPLC
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Pressure stability: 600 bar
• Eluent in column: Acetonitrile - Water
• L x Ø internal (column): 125 x 4.6 mm
• Pore volume: 0.9 ml/g
• Column type: HPLC column
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Temperature stability: 60 ° C
• pH stability: 1,0-11,0
• Column shape: Analytical separation column
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Column volume: 2.06 ml
• Specific surface according to BET: 340 m²/g
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Endcapped: yes
• Separation principle: Reversed phase (RP)
• Pore size: 110 Å
• USP listing: L1
• Particle size: 3 µm
• Phase: C 18 Gravity
• Particle type: Fully porous particles (FPP)