Produced for stability across temperature-sensitive applications, the HPLC column NUCLEODUR® C 18 Gravity offers an ideal solution for reversed phase separations, especially when working with basic and ionizable analytes. Its high density C 18 phase, based on high purity NUCLEODUR® silica gel, ensures reduced polar interactions, making it suitable for a wide range of applications including pharmaceuticals, pesticides, and herbicides. With enhanced pH stability, LC/MS suitability, and superior base deactivation, this column is an excellent choice for method development and RP applications. It features a particle size of 5 μm, a specific surface area of 340 m²/g, and a recommended operating temperature of up to 60°C.

• Category: Separation columns for HPLC
• L x Ø internal (column): 250 x 2 mm
• Pore size: 110 Å
• Temperature stability: 60 ° C
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Application Database (Macherey-Nagel): HPLC
• Specific surface according to BET: 340 m²/g
• Column type: HPLC column
• Pressure stability: 600 bar
• Particle size: 5 µm
• Column shape: Analytical separation column
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Particle type: Fully porous particles (FPP)
• USP listing: L1
• Separation principle: Reversed phase (RP)
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Phase: C 18 Gravity
• Endcapped: yes
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Pore volume: 0.9 ml/g
• Eluent in column: Acetonitrile - Water
• Column volume: 0.8 ml
• pH stability: 1,0-11,0