Formulated to support synthetic operations, the Hplc Column Nucleodur® PFP, 5 μm, 250 mm, 2 mm offers a versatile solution for separating aromatic and unsaturated compounds, antibiotics, halogenated compounds, isomers, pharmaceutical products, phenols, and especially polar compounds. Based on a high purity NUCLEODUR® silica gel, this reversed phase (RP) column features a pentafluorophenylpropyl (PFP) modification that provides an alternative selectivity compared to traditional C18 modifications. Its unique separation mechanism incorporates polar (H-bond), dipole-dipole, π-π, and hydrophobic interactions, making it suitable for LC/MS applications due to its low bleeding characteristics. With a specific surface area of 340 m²/g

• Category: Separation columns for HPLC
• Interactions / retention mechanism: polar (H-bond), dipole-dipole, π-π and hydrophobic
• Column type: HPLC column
• Specific surface according to BET: 340 m²/g
• Particle size: 5 µm
• L x Ø internal (column): 250 x 2 mm
• Column volume: 0.8 ml
• Pore volume: 0.9 ml/g
• Recommended application(s): Antibiotics Aromatic and unsaturated compounds Basic compounds Suitable for LC-MS Halogenated compounds Isomers Pharmaceutical products Phenols Especially for polar compounds
• pH stability: 1,0-9,0
• Pressure stability: 600 bar
• Separation principle: Reversed phase (RP)
• Pore size: 110 Å
• Eluent in column: Acetonitrile - Water
• Temperature stability: 60 ° C
• USP listing: L43
• Application Database (Macherey-Nagel): HPLC
• Surface chemistry: Pentafluorophenylpropyl (PFP) modification
• Particle type: Fully porous particles (FPP)
• Endcapped: yes
• Column shape: Analytical separation column
• Phase: PFP