HPLC column NUCLEODUR ® C 8 Gravity, 5 µm, 150 mm, 4.6 mm

Adapted for use across diverse chemical handling environments, the HPLC column NUCLEODUR® C 8 Gravity offers exceptional versatility in separating various compounds with ionizable functional groups. Its unique C 8 Gravity phase, based on high purity NUCLEODUR® silica gel, features endcapping that minimizes unwanted polar interactions, making it an ideal choice for the separation of basic and other ionizable analytes. With enhanced pH stability, LC/MS suitability, and superior base deactivation, this column is indispensable for method development and excels in reversed phase (RP) applications.

• Category: Separation columns for HPLC
• Phase: C 8 Gravity
• Eluent in column: Acetonitrile - Water
• Column volume: 2.5 ml
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Particle type: Fully porous particles (FPP)
• Temperature stability: 60 ° C
• Separation principle: Reversed phase (RP)
• USP listing: L7
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Pore volume: 0.9 ml/g
• Pore size: 110 Å
• Particle size: 5 µm
• Column type: HPLC column
• L x Ø internal (column): 150 x 4.6 mm
• Pressure stability: 600 bar
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Specific surface according to BET: 340 m²/g
• Column shape: Analytical separation column
• Application Database (Macherey-Nagel): HPLC
• Endcapped: yes
• pH stability: 1,0-11,0
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals