Designed with efficiency in synthetic processes in mind, this HPLC column Nucleodur® C 8 Gravity features fully porous particles (FPP) with a particle size of 5 μm and an internal length of 125 mm x 2 mm. Its high density C 8 phase, based on high purity Nucleodur® silica gel, offers excellent pH stability ranging from 1 to 11, making it ideal for separating basic and other ionizable analytes. With a specific surface area of 340 m²/g, this column provides ample interaction sites for hydrophobic (van der Waals) interactions, ensuring optimal retention mechanisms. Additionally, its endcapping feature suppresses unwanted polar interactions, enhancing its suitability for LC/MS applications and method development. This analytical separation column comes complete with an instruction leaflet and certificate of analysis

• Category: Separation columns for HPLC
• Endcapped: yes
• Phase: C 8 Gravity
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Pore size: 110 Å
• Specific surface according to BET: 340 m²/g
• Particle size: 5 µm
• Column type: HPLC column
• Separation principle: Reversed phase (RP)
• pH stability: 1,0-11,0
• Column volume: 0.37 ml
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Particle type: Fully porous particles (FPP)
• USP listing: L7
• Column shape: Analytical separation column
• Interactions / retention mechanism: hydrophobic (van der Waals)
• L x Ø internal (column): 125 x 2 mm
• Pressure stability: 600 bar
• Pore volume: 0.9 ml/g
• Application Database (Macherey-Nagel): HPLC
• Temperature stability: 60 ° C
• Eluent in column: Acetonitrile - Water