Formulated to support synthetic operations, the Separation columns for HPLC, specifically the HPLC column NUCLEODUR ® C 18 Gravity, 10 μm, 250 mm, 21 mm, offer an ideal solution for reversed phase (RP) separations. With a high density C 18 phase based on high purity NUCLEODUR ® silica gel, this column effectively suppresses unwanted polar interactions between the silica surface and the sample, making it particularly suitable for the separation of basic and other ionizable analytes. Its enhanced pH stability, LC/MS suitability, and superior base deactivation make it a valuable asset for RP applications, especially during method development. The column's specifications include a particle size of 10 μm, a pore size of 110 Å, and a temperature stability of 60

• Category: Separation columns for HPLC
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Particle size: 10 µm
• Pore volume: 0.9 ml/g
• pH stability: 1,0-11,0
• Endcapped: yes
• Pore size: 110 Å
• Column type: HPLC column
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Column volume: 87 ml
• Eluent in column: Acetonitrile - Water
• Particle type: Fully porous particles (FPP)
• Phase: C 18 Gravity
• Column shape: Preparative separation column
• L x Ø internal (column): 250 x 21 mm
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Temperature stability: 60 ° C
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Specific surface according to BET: 340 m²/g
• USP listing: L1
• Separation principle: Reversed phase (RP)
• Pressure stability: 400 bar