Engineered to maintain reliability in process-driven workflows, the Separation columns for HPLC, specifically the HPLC column NUCLEODUR ® C 8 Gravity, boasts a high density C 8 phase based on high purity NUCLEODUR ® silica gel. Its endcapping feature suppresses unwanted polar interactions, making it ideal for separating basic and ionizable analytes. With enhanced pH stability, LC/MS suitability, and superior base deactivation, this column is an excellent choice for method development and valuable for RP applications.

• Category: Separation columns for HPLC
• Endcapped: yes
• L x Ø internal (column): 100 x 4 mm
• Column volume: 1.25 ml
• Separation principle: Reversed phase (RP)
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Pore volume: 0.9 ml/g
• Specific surface according to BET: 340 m²/g
• Pore size: 110 Å
• Particle type: Fully porous particles (FPP)
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Temperature stability: 60 ° C
• Particle size: 3 µm
• pH stability: 1,0-11,0
• Pressure stability: 600 bar
• USP listing: L7
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Column shape: Analytical separation column
• Eluent in column: Acetonitrile - Water
• Column type: HPLC column
• Phase: C 8 Gravity