Designed for professional use, these Separation columns for HPLC are specifically engineered for reversed phase separations. The HPLC Column NUCLEODUR ® C 18 Pyramid features fully porous particles (FPP) with a particle size of 5 μm and a specific surface area of 340 m²/g, ensuring optimal efficiency and reproducibility. This column's unique C 18 Pyramid phase, combined with polar endcapping, allows it to handle aqueous eluents effectively, making it ideal for analyzing very polar compounds such as pharmaceutical raw materials, organic acids, and penicillin antibiotics. With a pressure stability of up to 600 bar and temperature stability at 60 °C, this column offers robust performance under demanding conditions. The recommended applications include water-soluble vitamins, complexing agents

• Category: Separation columns for HPLC
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Eluent in column: Acetonitrile - Water
• Application Database (Macherey-Nagel): HPLC
• Phase: C 18 Pyramid
• USP listing: L1
• Particle type: Fully porous particles (FPP)
• Column volume: 1.25 ml
• Column shape: Analytical separation column
• Temperature stability: 60 ° C
• Particle size: 5 µm
• Endcapped: yes
• Separation principle: Reversed phase (RP)
• Pressure stability: 600 bar
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• L x Ø internal (column): 75 x 4.6 mm
• Pore volume: 0.9 ml/g
• Column type: HPLC column
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Specific surface according to BET: 340 m²/g
• Pore size: 110 Å
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• pH stability: 1,0-9,0