Designed with efficiency in synthetic processes in mind, the HPLC Column Nucleodur® C 18 Pyramid offers a unique solution for separating very polar compounds such as pharmaceutical raw materials, organic acids, penicillin antibiotics, and water-soluble vitamins. Its fully porous particles (FPP), 3 μm particle size, and 1.25 ml column volume ensure high pressure stability up to 600 bar and temperature resistance up to 60°C. The polar endcapping makes this C 18 phase suitable for aqueous eluents, making it ideal for applications requiring 100% aqueous eluents. This HPLC column is compatible with reversed phase (RP) separation principles and features hydrophobic and polar interactions (H bonds) for optimal retention mechanisms.

• Category: Separation columns for HPLC
• Column type: HPLC column
• L x Ø internal (column): 75 x 4.6 mm
• Specific surface according to BET: 340 m²/g
• Particle type: Fully porous particles (FPP)
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Endcapped: yes
• Separation principle: Reversed phase (RP)
• Column shape: Analytical separation column
• Pore size: 110 Å
• Phase: C 18 Pyramid
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Particle size: 3 µm
• Temperature stability: 60 ° C
• Eluent in column: Acetonitrile - Water
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Pressure stability: 600 bar
• USP listing: L1
• Column volume: 1.25 ml
• Pore volume: 0.9 ml/g
• pH stability: 1,0-9,0