Formulated to support synthetic operations, the Hplc Column Nucleodur® C 18 Pyramid, 5 μm, 250 mm, 2 mm offers exceptional performance in reversed phase liquid chromatography. Its fully porous particles (FPP), 5 μm particle size, and 110 Å pore size provide high efficiency and pressure stability up to 600 bar. The column's unique octadecyl (C 18 , ODS) modification with polar endcapping makes it suitable for aqueous eluents, broadening its applicability to various analytes such as pharmaceutical raw materials, very polar compounds, and water-soluble vitamins. With a specific surface area of 340 m²/g and a temperature stability of 60°C, this HPLC column ensures reliable results under diverse conditions.

• Category: Separation columns for HPLC
• Phase: C 18 Pyramid
• USP listing: L1
• Particle size: 5 µm
• L x Ø internal (column): 250 x 2 mm
• Application Database (Macherey-Nagel): HPLC
• Pressure stability: 600 bar
• Separation principle: Reversed phase (RP)
• Specific surface according to BET: 340 m²/g
• Pore size: 110 Å
• Pore volume: 0.9 ml/g
• Column type: HPLC column
• pH stability: 1,0-9,0
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Column shape: Analytical separation column
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Endcapped: yes
• Temperature stability: 60 ° C
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Eluent in column: Acetonitrile - Water
• Particle type: Fully porous particles (FPP)
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Column volume: 0.8 ml