Widely applied in chemical workflows, the HPLC column NUCLEOSHELL ® RP 18, available in a dimension of 150 mm x 4.6 mm with an internal diameter of 2.7 μm, features a high density C 18 phase based on core-shell technology silica gel particles. Endcapped to suppress unwanted polar interactions, this column is ideal for separating basic and ionizable analytes, offering enhanced pH stability, LC/MS suitability, and superior base deactivation. With a specific surface area of 90 m²/g, it excels in reversed phase (RP) applications, providing excellent performance for antibiotics, antidepressants, anti-inflammatory drugs, herbicides, immunosuppressants, phytopharmaceuticals, and is suitable for LC-MS. The

• Category: Separation columns for HPLC
• pH stability: 1,0-11,0
• Specific surface according to BET: 90 m²/g
• Pressure stability: 600 bar
• Application Database (Macherey-Nagel): HPLC
• Particle size: 2.7 µm
• Column volume: 2.5 ml
• Endcapped: yes
• Pore size: 90 Å
• Column shape: Analytical separation column
• Recommended application(s): Antibiotics Antidepressants Anti-inflammatory drugs Herbicides Immunosuppressants Phytopharmaceuticals Suitable for LC-MS
• Phase: RP 18
• Column type: HPLC column
• Particle type: Core-shell, superficially porous particles (SPP)
• Pore volume: 0.9 ml/g
• L x Ø internal (column): 150 x 4.6 mm
• Surface chemistry: High density monomeric octadecyl (C 18 , ODS) modification, Base deactivated (BDS)
• Eluent in column: Acetonitrile - Water
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Temperature stability: 60 ° C
• USP listing: L1
• Separation principle: Reversed phase (RP)