Designed with efficiency in synthetic processes in mind, this Separation column for HPLC, specifically the HPLC column NUCLEODUR ® C 18 Isis, boasts a particle size of 3 μm and a length of 50 mm, providing an ideal balance between resolution and speed. Its unique nonpolar crosslinked polymeric octadecyl (C 18 , ODS) modification offers high steric selectivity, making it particularly suitable for separating ( o , p , m -) substituted aromatics. With a recommended temperature stability of 60 ° C and pressure stability of 600 bar, this column is well-equipped to handle demanding synthetic conditions. Additionally, its specific surface area of 340 m²/g ensures optimal interaction and retention mechanisms, further enhancing its performance in reversed phase (RP) separations.

• Category: Separation columns for HPLC
• Phase: C 18 Isis
• pH stability: 1,0-10,0
• Column type: HPLC column
• Temperature stability: 60 ° C
• Eluent in column: Acetonitrile - Water
• Surface chemistry: Nonpolar crosslinked polymeric octadecyl (C 18 , ODS) modification, High steric selectivity
• Column shape: Analytical separation column
• L x Ø internal (column): 50 x 3 mm
• Particle type: Fully porous particles (FPP)
• Pressure stability: 600 bar
• USP listing: L1
• Pore size: 110 Å
• Separation principle: Reversed phase (RP)
• Specific surface according to BET: 340 m²/g
• Pore volume: 0.9 ml/g
• Interactions / retention mechanism: steric and hydrophobic
• Particle size: 3 µm
• Endcapped: yes
• Column volume: 0.35 ml
• Recommended application(s): Separation of positional and structural isomers Planar/non-planar molecules Steroids Suitable for LC-MS (o,p,m-)Substituted aromatics Fat-soluble vitamins Exceptional steric selectivity