Configured for stable performance in synthesis settings, the HPLC Column Nucleodur® C 18 Pyramid offers exceptional versatility due to its polar endcapping, making it suitable for aqueous eluents. With a particle size of 1.8 μm and a pore size of 110 Å, this UHPLC column provides a specific surface area of 340 m²/g, ensuring efficient separations. Its surface chemistry, featuring octadecyl (C 18, ODS) modification and polar endcapping, supports hydrophobic and polar interactions (H bonds), ideal for analyzing very polar compounds such as pharmaceutical raw materials, organic acids, penicillin antibiotics, and water-soluble vitamins.

• Category: Separation columns for HPLC
• USP listing: L1
• Pore size: 110 Å
• Pressure stability: 900 bar
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Particle type: Fully porous particles (FPP)
• Endcapped: yes
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Separation principle: Reversed phase (RP)
• Application Database (Macherey-Nagel): HPLC
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Specific surface according to BET: 340 m²/g
• pH stability: 1,0-9,0
• Pore volume: 0.9 ml/g
• Column type: UHPLC column
• Temperature stability: 60 ° C
• Column volume: 0.35 ml
• Phase: C 18 Pyramid
• L x Ø internal (column): 50 x 3 mm
• Eluent in column: Acetonitrile - Water
• Column shape: Analytical separation column
• Particle size: 1.8 µm